| A.P.S.R.T.C Bus Route | Bus Type | Departure | Arrival | Boarding From |
| Tirupathi - Manthralayam Via Emmiganur | Exp | 0430 Hrs | 0545 Hrs | Tirupathi Bus Depot |  |
| Tirupathi - Manthralayam Via Gty - Adn | Exp | 0130 Hrs | 0545 Hrs | Tirupathi Bus Depot | |
| Tirupathi - Manthralayam Via Kdr - Atp | Exp | 2245 Hrs | 0545 Hrs | Tirupathi Bus Depot | |
| Tirupathi - Manthralayam Via Kdr - Atp - Gty - Adn | Exp | 2105 Hrs | 0545 Hrs | Tirupathi Bus Depot | |
| Tirupathi - Manthralayam Via Mpl - Atp - Gty - Adn | Exp | 1800 Hrs | 0545 Hrs | Tirupathi Bus Depot | |
There are 5 buses in a day between Tirupathi and Manthralayam. The first bus to depart is at 0430 Hrs by A.P.S.R.T.C. This bus is Exp and the boarding point is Tirupathi Bus Depot. The journey takes 1 Hrs covering a distance of 53 Kms and the bus will reach Manthralayam at 0545 Hrs
The next bus to depart is at 0130 Hrs by A.P.S.R.T.C. This bus is Exp and the boarding point is Tirupathi Bus Depot. The journey takes 4 Hrs covering a distance of 178 Kms and the bus will reach Manthralayam at 0545 Hrs
The next bus to depart is at 2245 Hrs by A.P.S.R.T.C. This bus is Exp and the boarding point is Tirupathi Bus Depot. The journey takes 7 Hrs covering a distance of 270 Kms and the bus will reach Manthralayam at 0545 Hrs
The last bus to depart is at 1800 Hrs by A.P.S.R.T.C. This bus is Exp and the boarding point is Tirupathi Bus Depot. The journey takes 11 Hrs covering a distance of 473 Kms and the bus will reach Manthralayam at 0545 Hrs