| A.P.S.R.T.C Bus Route | Bus Type | Departure | Arrival | Boarding From |
| Manuguru - Tirupathi Via Npt - Skht | Sl | 0230 Hrs | 0510 Hrs | Manuguru Bus Depot |  |
| Manuguru - Tirupathi Via Npt - Skht | Exp | 1605 Hrs | 1915 Hrs | Manuguru Bus Depot | |
| Manuguru - Tirupathi Via Nlr - Skht | Exp | 1300 Hrs | 1915 Hrs | Manuguru Bus Depot | |
| Manuguru - Tirupathi Via Nlr - Skht | Sl | 2340 Hrs | 0510 Hrs | Manuguru Bus Depot | |
| Manuguru - Tirupathi Via Ongl - Nlr | Sl | 2015 Hrs | 0510 Hrs | Manuguru Bus Depot | |
| Manuguru - Tirupathi Via Ong - Nlr | Exp | 0915 Hrs | 1915 Hrs | Manuguru Bus Depot | |
| Manuguru - Tirupathi Via Tvr - Vja - Ong - Nlr | Sl | 1645 Hrs | 0510 Hrs | Manuguru Bus Depot | |
| Manuguru - Tirupathi Via Tvr - Vja - Ong - Nlr | Exp | 0500 Hrs | 1915 Hrs | Manuguru Bus Depot | |
There are 8 buses in a day between Manuguru and Tirupathi. The first bus to depart is at 0230 Hrs by A.P.S.R.T.C. This bus is Sl and the boarding point is Manuguru Bus Depot. The journey takes 3 Hrs covering a distance of 124 Kms and the bus will reach Tirupathi at 0510 Hrs
The next bus to depart is at 1605 Hrs by A.P.S.R.T.C. This bus is Exp and the boarding point is Manuguru Bus Depot. The journey takes 3 Hrs covering a distance of 130 Kms and the bus will reach Tirupathi at 1915 Hrs
The next bus to depart is at 1300 Hrs by A.P.S.R.T.C. This bus is Exp and the boarding point is Manuguru Bus Depot. The journey takes 6 Hrs covering a distance of 254 Kms and the bus will reach Tirupathi at 1915 Hrs
The last bus to depart is at 0500 Hrs by A.P.S.R.T.C. This bus is Exp and the boarding point is Manuguru Bus Depot. The journey takes 14 Hrs covering a distance of 543 Kms and the bus will reach Tirupathi at 1915 Hrs