| A.P.S.R.T.C Bus Route | Bus Type | Departure | Arrival | Boarding From |
| Hyderabad (Mgbs) - Madhira Via Wyra | Exp | 0000 Hrs | 0120 Hrs | Hyderabad Bus Depot |  |
| Hyderabad (Mgbs) - Madhira Via Wyra | Dlx | 0400 Hrs | 0520 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Wyra | Exp | 1200 Hrs | 1340 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Wyra | Exp | 1600 Hrs | 1730 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Wyra | Exp | 1815 Hrs | 1935 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Wyra | Exp | 1900 Hrs | 2020 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Wyra | Exp | 2030 Hrs | 2150 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Wyra | Exp | 2115 Hrs | 2235 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Wyra | Exp | 0145 Hrs | 0305 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Wyra | Dlx | 0245 Hrs | 0405 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Wyra | Sl | 1645 Hrs | 1805 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Wyra | Exp | 2140 Hrs | 2300 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Exp | 0015 Hrs | 0305 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Dlx | 0115 Hrs | 0405 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Dlx | 0230 Hrs | 0520 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Exp | 1030 Hrs | 1340 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Exp | 1425 Hrs | 1730 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Sl | 1515 Hrs | 1805 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Exp | 1645 Hrs | 1935 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Exp | 1730 Hrs | 2020 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Exp | 1855 Hrs | 2150 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Exp | 1945 Hrs | 2235 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Exp | 2015 Hrs | 2300 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Exp | 2230 Hrs | 0120 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Exp | 0715 Hrs | 1340 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Exp | 1115 Hrs | 1730 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Sl | 1200 Hrs | 1805 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Exp | 1330 Hrs | 1935 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Exp | 1415 Hrs | 2020 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Exp | 1540 Hrs | 2150 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Exp | 1630 Hrs | 2235 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Exp | 1700 Hrs | 2300 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Exp | 1910 Hrs | 0120 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Exp | 2100 Hrs | 0305 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Dlx | 2200 Hrs | 0405 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Dlx | 2315 Hrs | 0520 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Wyra | Exp | 0500 Hrs | 2020 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Kmm - Wyra | Exp | 0330 Hrs | 2020 Hrs | Hyderabad Bus Depot | |
| Hyderabad (Mgbs) - Madhira Via Srpt - Kmm - Wyra | Exp | 0015 Hrs | 2020 Hrs | Hyderabad Bus Depot | |
There are 39 buses in a day between Hyderabad and Madhira. The first bus to depart is at 0000 Hrs by A.P.S.R.T.C. This bus is Exp and the boarding point is Hyderabad Bus Depot. The journey takes 1 Hrs covering a distance of 58 Kms and the bus will reach Madhira at 0120 Hrs
The next bus to depart is at 0400 Hrs by A.P.S.R.T.C. This bus is Dlx and the boarding point is Hyderabad Bus Depot. The journey takes 1 Hrs covering a distance of 58 Kms and the bus will reach Madhira at 0520 Hrs
The next bus to depart is at 1200 Hrs by A.P.S.R.T.C. This bus is Exp and the boarding point is Hyderabad Bus Depot. The journey takes 1 Hrs covering a distance of 58 Kms and the bus will reach Madhira at 1340 Hrs
The last bus to depart is at 0015 Hrs by A.P.S.R.T.C. This bus is Exp and the boarding point is Hyderabad Bus Depot. The journey takes 20 Hrs covering a distance of 261 Kms and the bus will reach Madhira at 2020 Hrs