| A.P.S.R.T.C Bus Route | Bus Type | Departure | Arrival | Boarding From |
| Ananthapur - Chennai Via Kanchi | Sl | 0215 Hrs | 0545 Hrs | Ananthapur Bus Depot |  |
| Ananthapur - Chennai Via Ptr - U Kottai | Sl | 0500 Hrs | 0830 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Kanchi | Sl | 0330 Hrs | 0700 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Ptr - U Kottai | Sl | 0430 Hrs | 0800 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Ctre | Sl | 2345 Hrs | 0545 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Ctre | Sl | 0045 Hrs | 0700 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Tpt | Sl | 0100 Hrs | 0800 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Tpt | Sl | 0130 Hrs | 0830 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Mdpl - Ctre | Sl | 2115 Hrs | 0545 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Mdpl - Ctre | Sl | 2215 Hrs | 0700 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Mdpl - Tpt | Sl | 2300 Hrs | 0800 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Mdpl - Tpt | Sl | 2330 Hrs | 0830 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Mdpl - Ctre | Sl | 1900 Hrs | 0545 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Mdpl - Ctre | Sl | 2000 Hrs | 0700 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Kdr - Mdpl - Tpt | Sl | 2100 Hrs | 0800 Hrs | Ananthapur Bus Depot | |
| Ananthapur - Chennai Via Kdr - Mdpl - Tpt | Sl | 2130 Hrs | 0830 Hrs | Ananthapur Bus Depot | |
There are 16 buses in a day between Ananthapur and Chennai. The first bus to depart is at 0215 Hrs by A.P.S.R.T.C. This bus is Sl and the boarding point is Ananthapur Bus Depot. The journey takes 3 Hrs covering a distance of 173 Kms and the bus will reach Chennai at 0545 Hrs
The next bus to depart is at 0500 Hrs by A.P.S.R.T.C. This bus is Sl and the boarding point is Ananthapur Bus Depot. The journey takes 3 Hrs covering a distance of 137 Kms and the bus will reach Chennai at 0830 Hrs
The next bus to depart is at 0330 Hrs by A.P.S.R.T.C. This bus is Sl and the boarding point is Ananthapur Bus Depot. The journey takes 4 Hrs covering a distance of 173 Kms and the bus will reach Chennai at 0700 Hrs
The last bus to depart is at 2130 Hrs by A.P.S.R.T.C. This bus is Sl and the boarding point is Ananthapur Bus Depot. The journey takes 11 Hrs covering a distance of 431 Kms and the bus will reach Chennai at 0830 Hrs