| Travel Agency | Bus Type | Boarding Point | Departure | Droping Point | Arrival |
| Sri Kannathal Travels | 2+2 Semi Sleeper | "Opp T.Nagar Bus Stand,T.Nagar,Chennai- 60" | 06:45 PM | "Corpration commercial complex, Kovilam Road,Karaikudi" | 06:00 AM |  |
| P R R Travels | Hi-tech- Airbus Non AC | "Royal Cabs,No:17, Narayanappa Nayakan St, Mannady, Chennai- 600" | 07:00 PM | "Kalyansundarm,81, Koviloor Road,Karaikudi." | 06:00 AM | |
| Parveen Travels | 2+2 Semi Sleeper | Near Omni Bus Ter | 07:15 PM | Near Bus Stand | 06:00 AM | |
| Parveen Travels | 2x2 Hi-Tech Semi Sleeper - Non A/c | "Shop No.49, Private Bus Terminus, Chennai- 600 092. Tami" | 07:15 PM | Near Bus Stand | 08:15 PM | |
| NarayanaMoorthy Travels | 2+2 Semi Sleeper | "Shop No:7, Omni Bus Terminus, Koya" | 08:00 PM | Karaikudi | 05:30 AM | |
| P.R.Travels | 2+2 Executive Air Bus | "Shop No:40, Omni Bus Terminus, Koya" | 08:30 PM | Karaikudi | 06:00 AM | |
| Parveen Travels | 2+2 A/C Coach | Near Omni Bus Ter | 10:00 PM | Near Bus Stand | 06:00 AM | |
| Parveen Travels | 2x2 -King Long -Semi Sleeper A/C | "Shop No.49, Private Bus Terminus, Chennai- 600 092. Tami" | 10:00 PM | Near Bus Stand | 08:15 PM | |
There are 8 buses in a day between Chennai and Karaikudi. The first bus to depart is at 06:45 PM by Sri Kannathal Travels. This bus is 2+2 Semi Sleeper and the exact address for pick up is "Opp T.Nagar Bus Stand,T.Nagar,Chennai- 60". This boarding point is called T Nagar and the landmark near is Near Krishnaveni Theatre. The journey takes 12 hours and the fare is starts from Rs. 300/-. This bus will reach Karaikudi at 06:00 AM and the exact address for drop is "Corpration commercial complex, Kovilam Road,Karaikudi" The drop point is called Golden Singer Town and the landmark near is Near Old Bus Stand
The next bus is at 07:00 PM by P R R Travels. This bus is Hi-tech- Airbus Non AC and the exact address for pick up is "Royal Cabs,No:17, Narayanappa Nayakan St, Mannady, Chennai- 600". This boarding point is called Chennai and the landmark near is Narayanappa Nayakan st. The journey takes 11 hours and the fare is starts from Rs. 350/-. This bus will reach Karaikudi at 06:00 AM and the exact address for drop is "Kalyansundarm,81, Koviloor Road,Karaikudi." The drop point is called Golden Singer Town and the landmark near is Koviloor Road
The next bus is at 07:15 PM by Parveen Travels. This bus is 2+2 Semi Sleeper and the exact address for pick up is Near Omni Bus Ter. This boarding point is called Koyambedu and the landmark near is Omni Bus Terminus. The journey takes 11 hours and the fare is starts from Rs. 330/-. This bus will reach Karaikudi at 06:00 AM and the exact address for drop is Near Bus Stand The drop point is called Golden Singer Town and the landmark near is Bus Stand
The last bus is at 10:00 PM by Parveen Travels. This bus is 2+2 A/C Coach and the exact address for pick up is Near Omni Bus Ter. This boarding point is called Koyambedu and the landmark near is Omni Bus Terminus. The journey takes 8 hours and the fare is starts from Rs. 410/-. This bus will reach Karaikudi at 06:00 AM and the exact address for drop is Near Bus Stand The drop point is called Golden Singer Town and the landmark near is Bus Stand